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C-H activation


“C-H activation” refers to reactions involving the cleavage of an unreactive C-H bond of alkanes, arenes, or alkyl chains by transition metal complexes to form products with M-C bond.

Enantio-selective synthesis


Enantioselective synthesis, also called chiral synthesis or asymmetric synthesis, is a form of chemical synthesis. It is defined by IUPAC as: a chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric (enantiomeric or diastereoisomeric) products in unequal amounts.


Unconventional green Synthesis


Green Chemistry is the design of chemical products and processes that reduce or eliminate the use and/or generation of hazardous substances.

1.Green chemistry can also be described as

2.Sustainable chemistry.

3.Chemistry that is benign by design.

4.Pollution prevention at the molecular level.

5.Solvents free reaction

6.All of the above.


Molecular machines


What would be the utility of such machines? Who knows? I cannot see exactly what would happen, but I can hardly doubt that when we have some control of the arrangement of things on a molecular scale we will get an enormously greater range of possible properties that substances can have, and of the different things we can do. What would be the utility of such machines? Who knows? I cannot see exactly what would happen, but I can hardly doubt that when we have some control of the arrangement of things on a molecular scale we will get an enormously greater range of possible properties that substances can have, and of the different things we can do A machine is “an apparatus for applying mechanical power, having several part each with a definite function”.



A molecular-level machine can be defined as an assembly of a discrete number of molecular components designed to perform mechanical-like movements (output) as a consequence of appropriate external stimuli (input).


Multicomponent Synthesis


Multicomponent Reactions (MCRs) are convergent reactions, in which three or more starting materials react to form a product, where basically all or most of the atoms contribute to the newly formed product.


Organocatalysis

Organocatalysis is the acceleration of chemical reactions with a substoichiometric amount of an organic compound which does not contain a metal atom.


Organocatalysis offers several advantages. There is no need for metal-based catalysis thus making a contribution to green chemistry. In this context, simple organic acids have been used as catalyst for the modification of cellulose in water on multi-ton scale. When the organocatalyst is chiral an avenue is opened to asymmetric catalysis, for example the use of proline in aldol reactions is an example of chirality and green chemistry.


Polymeric materials synthesis


A polymer is a large molecule, or macromolecule, composed of millions of repeated linked units, each a relatively light and simple molecule. Because of their broad range of properties, both synthetic and natural polymers play an essential and ubiquitous role in everyday life.These polymeric materials have some advantages like easy processing, high ductility, light products, thermal insulator, electic insulators etc and applications in products of elevated consumption, automobile, aeronautics, aerospace construction, coatings for wires, developing of nonlinear optics, etc.


NCE in drug Synthesis



A new chemical entity (NCE) is a novel chemical compound developed in the early drug discovery stage, and it could be optimized into a drug for diagnosis, treatment, or prevention of a disease.


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