Department of Biotechnology,Indian Institue of Technology Roorkee
Dr. Kiran Ambatipudi
Srinivas Kiran Ambatipudi Associate professor +91-1332-284786
Areas of Interest
  • Application of proteomics in elucidate the role of milk proteins in the pathophysiology of animal disease, Investigate the role of salivary proteins in breast cancer progression
Professional Background
2013-08-122014-01-15ScientistVaccine Production Program Laboratory, National Institutes of Health, Bethesda, USA
2013-06-242013-08-09Senior ScientistEurofins Medinet, Chantilly, USA
2010-06-212013-02-15Research FellowDental and Craniofacial Institute, National Institutes of Health, Bethesda, USA
2007-08-152010-06-18Postdoctoral Research AssociateSchool of Medicine and Dentistry, University of Rochester, Rochester, USA
2005-01-012007-01-01InstructorSchool of Biological Sciences, Macquarie University, Sydney, Australia
Multiple Posts
2020-08-10OngoingAssociate ProfessorIndian Institute of Technology Roorkee
2020-01-01OngoingAssociate Dean of Students' Welfare (Student Wellness)Indian Institute of Technology Roorkee
2018-01-01OngoingFaculty AdvisorE Summit, Indian Institute of Technology Roorkee
2016-01-01OngoingMember DRC (Departmental Research CommitteeDept. of Biotechnology, Indian Institute of Technology Roorkee
2014-01-172020-08-10Assistant ProfessorDepartment of Biotechnology, Indian Institute of Technology, Roorkee, India
2018-07-012020-06-30Chief WardenRajiv Bhawan, Indian Institute of Technology Roorkee
2016-07-012018-06-30WardenRajiv Bhawan, Indian Institute of Technology Roorkee
2016-07-012017-06-30Staff Advisor Students Club, CricketIndian Institute of Technology Roorkee
Honors and Awards
Selected as a panel member for "Scientific Panel of Antibiotic Residues"Food Safety and Standards Authority of India, Ministry of Health and Family Welfare2020
International travel support(DST-SERB)65th American society of mass spectrometry, Indianapolis, USA2017
2nd Prize in Oral PresentationInternational Conference in Genomics and Proteomics2014
Travel Fellowship for Oral PresentationInternational Society for Developmental and Comparative Immunology, Charleston, USA2006
Awarded with Travel Fellowship in the year 2006 during the work at Macquarie University Travel GrantMacquarie University2005
Travel Fellowship for Oral PresentationInternational Society for Wild Life Disease, Cairns, Australia2005
Travel Fellowship for Poster PresentationAustralian Peptide Conference, Hamilton Island, Australia2005
Travel Fellowship for Poster PresentationLorne Protein Conference, Philip Island, Australia2005
Educational Details
PhDBiological SciencesMacquarie University, Sydney, Australia2007
MScApplied GeneticsUniversity of Birmingham, Birmingham, UK2003
BVSc. & AHVeterinary ScienceOdisha University of Agriculture and Technology2002
Sponsored Research Projects
TopicFunding AgencyStart DatePeriod
Bovine milk fat globule characterizationDBT2020-081 month
Bovine milk glycoproteomicsDST-SERB2016-083 years 2 months
Lipidomics of bovine milk under different seasons and feedsDBT2015-093 years
Quantitative proteomics of milk proteins in bovine mastitisMHRD2014-043 years
  • Odisha Veterinary Council, Member
  • Proteomics Society of India, Life Membership
Teaching Engagements
TitleCourse CodeClass NameSemester
Genomics and ProteomicsBTN-441B Tech Year 3Spring
Good Laboratory Practices and BioethicsBTN-636Pre-PhDSpring
Technical CommunicationBTN-524MSc and Pre-PhDSpring
Animal BiotechnologyBTN-305B Tech - Year 3Autumn
Technical CommunicationBTN-391B Tech- Year 3Autumn
Research Scholar Groups
Scholar NameInterest
Kuldeep GiriSalivary Proteins in Breast Cancer Progression
Monica YadavHuman Milk and its Role in Modulation of Gut Microbiota
Ayushi KapoorBovine Milk in Breast Cancer Therapy
Vinod BishtDevelopment of Chemosresistance in Breast Cancer
Arpita DasCharacterization of bovine milk
PHDs Supervised
TopicScholar NameStatus of PHDRegistration Date
Isolation and Characterization of Bovine Milk LipidsAparna VermaA2014-07-15
Bovine milk characterization in clinical mastitisSudipa MaityA2016-01
Characterization of Bovine Milk in Health and DiseaseLovely Professional University (Webinar)2020-08-29
In-Depth Bovine Milk Analysis to Unearth Goldmine Beneficial for Health ApplicationsCollege of Veterinary Science and Animal Husbandry (National Webinar)2020-08-14
Human Saliva: Body’s Mirror in Health and Disease?ASEAN -INDIA Workshop on "Emerging Technologies for Young Biotech Professionals, IGIB, New Delhi2019-09-23
Proteomics in Veterinary Research: Bench-to-Pen SideNTR College of Veterinary Science, Sri Venkateswara University, Gannavaram, Andhra Pradesh, India2019-04-27
The Walk of Life in Biological Laboratory: Dos and Don’tsDepartment of Biochemistry, Panjab University, Chandigarh, India2018-03-12
Human Saliva: Body’s Mirror in Health and Disease?Institute of Life Science, Bhubaneswar, Odisha, India2017-03-20
Other work

- Journal Reviewer

1. Food Chemistry, 2. Food Research International, 3. PLoS ONE, 4. Journal of Food Engineering, and 4. BMC Veterinary Research

Books Authored

Book Chapter

1. Kuldeep Giri, Vinod Singh Bisht, Sudipa Maity, Kiran Ambatipudi (2020). Biotechnological Advances for Microbiology, Molecular Biology, and Nanotechnology: An Interdisciplinary Approach to the Life Sciences. Chapter 14, Apple Academic Press.

2. Marcelo A. Catalán, Kiran S. Ambatipudi and James E. Melvin. (2012). Salivary Gland Secretion. In: Physiology of the Gastrointestinal Tract. Chapter: 45, Elsevier. Editor: Leonard R. Johnson, Academic Press, 2012, pp. 1229-1250. 

Refereed Journal Papers

Since Joining IITR in 2014


1. Sudipa Maity, Debiprasanna Das, Kiran AmbatipudiQuantitative Alterations in Bovine Milk Proteome between  Healthy, Subclinical and Clinical Mastitis during S. aureus Infection. Journal of Proteomics,  223, 103815. 

2. Sudipa Maity, Aadil Bhat, Kuldeep Giri, Kiran Ambatipudi (2020). BoMiProt: A Database of Bovine Milk Proteins. Journal of Proteomics, 215, 103648.

3. Aparna Verma, Ajay K. Sharma, Ayushi Agarwal, Saurav Datta*, Kiran Ambatipudi(2020). Selective Enrichment of Milk fat Globules Using Functionalized Polyvinylidene Fluoride membrane. Preparative Biochemistry and Biotechnology, 50, 18-27. ¶ Equal Contribution; * Co-Corresponding Author



4. Aparna Verma, Tamoghna Ghosh, Bharat Bhushan, Gopinath Packirisamy, Naveen K. Navani, Pranita P. Sarangi, Kiran Ambatipudi (2019). Characterization of Difference in Structure and Function of Fresh and Mastitic Bovine Milk Fat Globules. PLoS One, 14 (8), e0221830.

5. Teotia D, Gaid M, Saini SS, Verma A, Yennamalli RM, Khare SP, Ambatipudi K, Mir JI, Beuerle T, Hänsch R, Roy P, Agrawal PK, Beerhues L, Sircar D. Cinnamate:CoA-ligase is involved in Benzoate-derived Biphenyl Phytoalexin Biosynthesis in Malus × domestica 'Golden Delicious' Cell Cultures. Plant J. 100, 1176-1192.

6. Sudipa Maity, Kiran Ambatipudi (2019)Quantitative Proteomics of Milk Whey Reveals Breed and Season Specific Variation in Protein Abundance in Holstein Friesian Cow and Murrah Buffalo. Research in Veterinary Science, 125, 244-252.

7. Kuldeep Giri, Anurag Mehta, Kiran Ambatipudi (2019). In search of the Altering Salivary Proteome in Metastatic Breast and Ovarian Cancer. FASEB BioAdvances, 1, 191-207. (In the top 10% of most downloaded papers  of FASEB BioAdvances Journal between January 2018-December 2019)

8. Aadil H. Bhat, Sudipa Maity, Kuldeep Giri, Kiran Ambatipudi (2019). Protein glycosylation: Sweet or Bitter for Bacterial Pathogens? Critical Reviews in Microbiology, 45, 82-102.



9. Atin Sharma, Vineet Dubey, Rajnikant Sharma, Kuldip Devnath, Vivek Kumar Gupta, Jawed Akhter, Timsy Bhando, AparnaVerma, Kiran Ambatipudi, Mihir Sarkar, Ranjana Pathania (2018). The unusual glycine rich C-terminus of the Acinetobacter baumannii RNA chaperone Hfq plays an important role in bacterial physiology. Journal of Biological Chemistry, 293, 13377-13388.

10. #Sarangi PP,  #Chakraborty P, Dash SP, Ikeuchi T, Vega SD, Ambatipudi K, Wahl L, *Yamada Y (2018). Cell adhesion protein Fibulin-7 and its C-terminal fragment negatively regulate monocyte and macrophage migration and functions in vitro and in vivo. FASEB Journal, 32, 4889-4898.



11Kumar P, Kesari P, Dhindwal S, Choudhary A.K., Katiki M, Neetu, Verma A, Ambatipudi K, Tomar S, Sharma A.K., Mishra G, Kumar P (2017). A novel function for globulin in sequestering plant hormone:Crystal structure of Wrightia tinctoria 11S globulin in complex with auxin. Scientific Reports, 7, 4705.



12. Aparna Verma and Kiran Ambatipudi (2016). Challenges and opportunities of bovine milk analysis by mass spectrometry. Clinical Proteomics, 13, 8. (Invited Review)



13. Shveta Bathla#; Preeti Rawat#; Rubina Baithalu; Munna Lal Yadav; Jasmine Naru; Anurag Tiwari; Sudarshan Kumar; Ashok K. Balhara; Surender Singh; Suman Chaudhary; Rajesh KumarPradip Behere; Sushil K. Phulia; Tushar K. Mohanty; Jai K. Kaushik; Shivramaiah Nallapeta; Inderjeet Singh; Srinivas K. Ambatipudi; Ashok K. Mohanty (2015). Profiling of cow urinary proteins using various extraction methods reveals more than 1550 proteins. Journal of Proteomics, S1874-3919, 30023-3. # (Equal Contribution).


Patents Filed

1. Srinivas Kiran Ambatipudi, Saurav Datta, Aparna Verma.“Functionalized membrane based Process for selective isolation and Enrichment of milk fat globules (MFGs)”. Indian Patent, Provisional application number: 201811013231 filed on April 6th2018.

2. Srinivas Kiran Ambatipudi and Aparna Verma. ‘A Bioconversion Process To Produce Bioactive Cordyceps Species From Food Waste’ Indian Patent, Provisional Patent no: application number ‘201811023344’filed on June 22nd2018.



1.  Peter Burbelo, Kiran Ambatipudi, Ilias Alevizos (2014). Genome-wide association studies in Sjögren’s Syndrome: what are the genes telling us about disease pathogenesis? Autoimmunity Reviews, 13, 756-761.

2. Kiran S. Ambatipudi* and James E. Melvin (2013). Cancer biomarker discovery in saliva by mass spectrometry.  (*Corresponding author), Oncology, Gastroenterology and Hepatology Reports, 2, 1-8.

3. Kiran S. AmbatipudiSteve Swatkoski, James J. Moresco, Patricia G. Tu, Andreea Coca, Jennifer H. Anolik, Marjan Gucek, Igñacio Sanz, John R. Yates III, James E. Melvin (2012). Quantitative proteomics of human parotid saliva  in primary Sjögren’s syndrome. Proteomics, 12, 1-8.

4.  Bassim CW*, Ambatipudi KS*, Mays JW, Edwards DA, Swatkoski S, Fassil H, Bird K, Gucek M, Melvin  JE, Pavletic SZ (2012). Quantitative salivary proteomics of oral chronic Graft-versus-Host Disease in humans. (*Co- First Author), Journal of Clinical Immunology, 32, 1390-9.

5.  Gregoire S, Silva BB, Gonzalez I, Agidi PS, Xiao J, Klein MI, Ambatipudi KS, Bauserman R, Waugh R, Koo H  (2011). A novel role for the glucosyltransferase B in Candida albicans interactions with Streptococcus mutans and      apatitic surfaces. Applied and Environmental Microbiology77, 6357-67.

6.  Kiran S. Ambatipudi, Fred K. Hagen, Claire Delahunty, Xuemei Han, Rubina Shafi, Jennifer Hryhorenko, Stacy Gregoire, Bob Marquis, James E. Melvin, Hyun M. Koo, John R Yates III (2010). Human Common Salivary Protein-1  (CSP-1) Promotes binding of Streptococcus mutans to experimental salivary pellicle and glucans formed on  hydroxyapatite surface. Journal of Proteome Research, 9, 6605-14.

7Kiran S. Ambatipudi, Bingwen Lu, Fred K. Hagen, James E. Melvin, John R. Yates III (2009). Quantitative analysis of age specific variation in the expression of human female parotid salivary proteins. Journal of Proteome Research, 8, 5093-5102. (Highlighted in the issue of J Proteome Res.).

8Kiran S. Ambatipudi and Elizabeth Deane (2008). Proteomic analysis of neutrophil granule proteins in the Tammar wallaby (Macropus eugenii). Molecular Immunology, 45; 690-700.

9.  Kiran S. Ambatipudi, Janice Joss, Mark Raftery and Elizabeth Deane (2008). A proteomic approach to analysis of antimicrobial activity in marsupial pouch secretions. Developmental and Comparative Immunology, 32; 108-20.

10.  Kiran S. Ambatipudi, Janice Joss and Elizabeth Deane (2007). A comparative proteomic   analysis of skin secretion of the tammar wallaby (Macropus eugenii) and the wombats (Vombatus ursinus). Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, (2); 322-331.

11. Kiran S. Ambatipudi, Julie Old, Michael Guilhaus, Mark Raftery, Lyn Hinds and Elizabeth Deane (2006). Proteomic analysis of neutrophil proteins in the Tammar wallaby (Macropus eugenii). Comparative Biochemistry and PhysiologyPart D: Genomics and Proteomics, (1): 283- 291.

12.  Pattanaik T. K., Nath I., Bose V. S. C., Kiran A. S. (2001). Bone plating of distal radioulnar fracture in a  dog. Indian   Journal of Veterinary SurgeryVol. 22(1): 59-60.

13.  Pattanaik T. K., Nath I., Bose V. S. C., Kiran A. S. (2001). Open reduction of elbow dislocation in a dog. Indian   Journal of Veterinary Surgery, Vol. 22(1): 63.



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