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Anuj Sharma, PHD
Anuj Sharma Associate Professor anujsfcy[at]iitr.ac.in 01332-284751 Website
Areas of Interest
  • organic synthesis, Multi Component Reactions, Micowave Assisted Organic Synthesis, homogeneous catalysis
  • medicinal chemistry, rational drug design, NTD, virtual and high throughput synthesis
Professional Background
FromToDesignationOrganisation
2015ongoingAssociate ProfessorIIT Roorkee
May 2011Nov 2015Assistant ProfessorIIT Roorkee
20072011Research Associate/research ScientistUniversity of Arizona, USA
20072007Post Doc FellowKU Leuven, Belgium
20062007Post Doc FellowUFSM
Honors and Awards
AwardInstituteYear
NIH Post Doctoral FellowshipUniversity of Arizona, USA2008-2011
Educational Details
DegreeSubjectUniversityYear
MScChemistryHPU Shimla2000
Administrative Background
FromToDesignationOrganisationLevel
Jan 2012May 2014Faculty advisorCultural council
Jan 2013June 2014WardenIIT Roorkee
20142015member, DACIIT R
20132016member, DPCIITR
2014ongoingOC, safetyIITR
Sponsored Research Projects
TopicFunding AgencyYear
Use of Glyoxalic acids in MCR reactionsDST2012
Synthesis of novel heterocycles using copper catalysed strategiesScience and Engineering Research Board2015
Novel heterocyclic compounds as therapeutic hits CSIR2013
Synthesis of Anti-malarial compoundsSRIC2012
Memberships
  • Indian council of chemists, Life member
  • American Chemical Society, Member
  • Royal Chemical Society, member
  • Indian Chemical Society, Life Member
Teaching Engagements
TitleCourse CodeClass NameSemester
Adv Organic ChemistryCY621(o)MSC FAutumn
Adv Analytical ChemistryCY631(A)MSC FAutumn
Pharmaceutical Organic SynthesisCYN-722MTechSpring
Organic ChemistryCYN-002BTechAutumn
Organic Chemistry-IICYN-203Integrated IInd yearAutumn
Research Scholar Groups
Scholar NameInterest
Tanpreet kaur (Post Doc Student)Isocyanide chemistry
Debsmita Sahaheterocyclic synthesis
Saurav BagchiMCR
Anuj Kumarheterocyclic synthesis
Preeti WadhwaMCR
Abdul Kadir Shaube (under International student exchange)Synthesis, med chem
PHDs Supervised
TopicScholar NameStatus of PHDRegistration Year
Design and synthesis of prospective antimalarials by [4+1] multicomponent reactionManoj KumarA2011
Design and synthesis of prospective chemotherapeutic agents Debasmita SahaO2012
Synthesis of novel heterocycles through MCR sequencesPreeti WadhwaO2013
Design and Synthesis of anti-cancer molecules Anuj KumarO2013
Design and synthesis of novel chemotherapeutic agents through MCR sequencesSaurav BagchiO2013
Design and Synthesis of novel heterocycles through sustainable chemistryAbdul Kadir Shaube (under International student exchange)O2015
Invitations
TopicOrganistaionCategoryYear
Drug Discovery: opportunity at the bottom of the pyramidCentral University GarhwalG2015
Rational Drug Design: A Paradigm of New Hope in Drug DiscoveryNIT HamirpurG2014
Annual National Conference on Science: Emerging Scenarios and Future ChallengesHim Science Congress AssociationG2014
Rational Drug Design in quest for novel putative drug candidates against tropical diseasesFRI ShimlaG2014
Refereed Journal Papers

Some Recent Publications:

  1. A multilayer screening approach toward the discovery of novel Pf-DHFR inhibitors, Sourav Bagchi, Manoj Kumar and Anuj Sharma*, Computational biology and chemistry, 2016, accepted.
  2. Isocyanide Based [4+1] Cycloaddition Reactions: An Indispensable Tool in Multi-Component Reactions (MCRs), Tanpreet Kaur, Preeti Wadhwa, Sourav Bagchi, and Anuj Sharma*, Chem Comm, 2016, accepted.
  3. Novel Furochromenone based Dual Channel Sensors for Selective Detection of Cu2 + with Potential Applications in Sample Monitoring, Membrane Sensing and Photo–printing, Manoj Kumar, Lokesh Kumar Kumawat, Vinod Kumar Gupta and Anuj Sharma* Chemistry Select, 2016, 2, 277-284.
  4. A Rapid One-Pot Five Component Sequential Access to Novel Imidazo[2,1-b]thiazinyl- a-aminophosphonates, Tanpreet Kaur, Debasmita Saha, Neetu Singh, Udai Pratap Singh and Anuj Sharma*, Chemistry Select, 2016, 3, 434-439.
  5. p-TSA mediated three component MCR "On-water" protocol towards synthesis of novel thiadiazolo[2,3-b]quinazolin-6(7H)-ones, Preeti Wadhwa, Tanpreet Kaur, Neetu Singh, Udai Pratap Singh and Anuj Sharma*, Asian J. Org. Chem., 2016, 5, 120-126.
  6. A novel domino four component reaction: an eco-compatible access to diversified Imidazo[2,1-b][1,3]thiazin-5-ones, Tanpreet Kaur, Preeti Wadhwa, and Anuj Sharma*, Asian J. Org. Chem., 2016, 5, 91-97.
  7. A Rapid Access to Novel Thiazepinyl and Oxazepinyl Phosphonates through a Green Pudovik Reaction, Debasmita Saha, Tanpreet Kaur, Neetu Singh, Udai Pratap Singh and Anuj Sharma*, Asian J. Org. Chem., 2016, 5, 82-90.
  8. 3D-QSAR Selectivity Analysis of 1-Adamantyl-3-Heteroaryl Urea Analogs as Potent Inhibitors of Mycobacterium tuberculosis, Preeti Wadhwa, Sourav Bagchi, Anuj Sharma*, Curr. Comput. Aided Drug Des., 2015, 11, 164-183.
  9. Rational designing of first furoquinolinol based molecular systems for easy detection of Cu2+ with potential applications in the area of membrane sensing, Manoj Kumar, Lokesh Kumar Kumawat, Vinod Kumar Gupta and Anuj Sharma*, RSC Adv., 2015, 5, 106030-106037.
  10. Combined 3D-QSAR and Molecular Docking Study for the Identification of Diverse Natural Products as Potent Pf ENR Inhibitors,  Preeti Wadhwa, Debasmita Saha, and Anuj Sharma*, Curr. Comput. Aided Drug Des., 2015, 11, 245-257.
  11. First vinyl acetate mediated organocatalytic transesterification of Phenols: A step towards sustainability,  Manoj Kumar, Sourav Bagchi and Anuj Sharma*, New J. Chem., 2015, 39, 8329 - 8336.
  12. Microwave assisted synthesis of benzenesulfonohydrazide and benzenesulfonamide cyclic imide hybrid molecules and their evaluation for anticancer activity, Anuj Kumar, Nikhil Kumar, Partha Roy, S. M. Sondhi and Anuj Sharma*, Med. Chem. Res., 2015, 24, 3760-3771.
  13. CoMFA/CoMSIA based 3D-QSAR studies of 1-adamantyl-3-heteroaryl urea analogs as potent inhibitors of Mycobacterium tuberculosis, Preeti Wadhwa, Sourav Bagchi and Anuj Sharma*, Curr. Comput. Aided Drug Des., 2015,11,164-83.
  14. Benzothiazepines: Chemistry of a privileged scaffold, Debasmita Saha, Garima Jain, Anuj Sharma*, RSC Adv., 2015, 5, 70619.
  15. Arylsulfonylmethyl isocyanides: A Novel Paradigm in Organic Synthesis, T. Kaur, P. Wadhwa, A. Sharma*, RSC Adv., 2015, 5, 52769.
  16. A First Catalyst and Solvent-Free Synthesis of 2-Arylimidazo[2,1-b][1,3,4]thiadiazoles: A Comparative Assessment of Greenness,  P. Wadhwa, T. Kaur, A. Sharma*, RSC Adv., 2015, 05, 44353.
  17. 2-(Alkylamino)-3-aryl-6,7-dihy drobenzofuran-4( 5H)-ones : Improved Synthesis and their Photophysical Properties, M. Kumar, L. K. Kumawat, V. K. Gupta and A. Sharma*, Chem. Open, 2015, 4, 626.
  18. Vinyl esters as effective acetaldehyde surrogates in [4 + 1] cycloaddition based multicomponent cascade, M. Kumar, S. Bagchi and A. Sharma*, RSC Adv., 2015, 05, 53592.
  19. A sequential synthetic strategy towards unexplored dibenzo[b,f][1,4]thiazepine carboxamides: copper catalysed C-S cyclisation followed by Ugi type 3CC Cascade, Debasmita Saha, Preeti Wadhwa and Anuj Sharma*, RSC Adv., 2015, 05, 33067.
  20. Silica supported glyoxylic acid: a traceless, green approach to Groebke-Blackburn-Bienymé reaction, Pritam Surkar, Tanpreet Kaur and Anuj Sharma*, Synlett, 2015, 26, 1403. 
  21. Synthesis of acridine cyclic imide hybrid molecules and their evaluation for anticancer activity, Anuj Kumar, Nikhil Kumar, Partha Roy, S. M. Sondhi and Anuj Sharma*, Med. Chem. Res., 2015, 24, 3272.
  22. A green, catalyst-free, solvent-free, high yielding one step synthesis of functionalized benzo[f]furo[3,2-c]chromen-4-(5H)-ones and furo[3,2-c]quinolin-4-(5H)-ones, Manoj Kumar,  Tanpreet Kaur, Vinod Kumar Gupta and Anuj Sharma*, RSC Adv., 2015, 5, 17087.
  23. Debasmita Saha and Anuj Sharma*, Med. Chem. Res., 2015, 24, 316–333.
  24. In-silico investigation of medicinal spectrum of imidazo-azines from the perspective of multi-target screening against Malaria, Tuberculosis and Chagas disease, Manoj Kumar, Barnita Makhal, Vinod K. Gupta and Anuj Sharma*, J. Mol. Info.Mod., 2014, 50:1-9.
  25. In-silico docking studies of bioactive natural plant products as putative DHFR antagonists, Manoj Kumar, Anuradha, Vinod K. Gupta and Anuj Sharma*, Med. Chem. Res., 2014, 23:810–817.