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Sulakshana P. Mukherjee
Sulakshana P. Mukherjee Assistant Professor mukherji.fbt[at] +91-133228-4813
Areas of Interest
  • Structural and Molecular Biology: Protein-protein, Protein-DNA interaction, :-------using NMR, various biophysical and biochemical methods
Professional Background
2014presentAssistant ProfessorIIT-Roorkee
20132014Research AssociateThe Scripps Research Institute, California
20132014Visiting ScholarUniversity of California, San Diego
20112013Assistant Research ScientistUniversity of California, San Diego
20112011Professional Scientific CollaboratorThe Scripps Research Institute, California
20062011Post doctoral FellowUniversity of California, San Diego
20052005Visiting ScholarUniversity at Buffalo, The State University of New York
Honors and Awards
Irvington Institute Postdoctoral FellowshipCancer Research Institute2009-2012
TAA-Zita Lobo Memorial Award for the best thesis of the yearTata Institute of Fundamental Research2007
Sarojini Damodaran International FellowshipTata Institute of Fundamental Research2005
Best oral presentation awardRSC-West India Section2005
Educational Details
PhDChemical SciencesTata Institute of Fundamental Research, Mumbai2006
MScInorganic ChemistryMumbai University2000
BScChemistryMumbai University1998
Administrative Background
2015CurrentWardenKastuba Bhawan
Participation in seminars
NamePlaceSponsored ByDate
Structure-Function Analysis of NF-kappaB interactions in transcription regulationTIFR, MumbaiTIFR, MumbaiOct 2015
Structural basis for the functional role of RelA:CBP/p300 interaction in RelA driven transcriptionUniversity of California, San DiegoCancer/Mammals clubJune 2013
Insights into the RelA:CBP interaction in transcription regulationWhistler, CanadaKeystone symposia: NF-kappaB Signaling and Biology: From Bench to BedsideMar 2012
Magnesium promotes conformational switching action of a calcium sensor proteinPune, IndiaRSC-West India Section Student Sumposium-05Nov 2005
Structural characterization of the apo-form of a EF-hand calcium binding protein and its equilibriumHyderabad, IndiaXX ICMRBSJan 2005
  • National Magnetic Resonance Society of India, Life Member
  • Indian Biophysical Society, Life Member
Teaching Engagements
TitleCourse CodeClass NameSemester
NMR in Medicine and BiologyBT-640PGSpring
Molecular BiophysicsBTN-442UGAutumn
Molecular BiophysicsBTN-521PGSpring
Research Scholar Groups
Scholar NameInterest
Tahseen RazaMolecular Biophysics
Manish KumarMolecular Biophysics
Refereed Journal Papers
  1. Mukherjee SP, Quintas PO, McNulty R, Komives EA, Dyson HJ. Structural characterization of the ternary complex that mediates termination of NF-kB signaling by IkBa. (2016) Proc Natl Acad Sci USA 113:6212-7
  2. Mukherjee SP, Borin B, Quintas PO, Dyson HJ. NMR Characterization of a 72 kDa transcription factor using differential isotopic labeling. (2016) Protein Sci. 25:597-604
  3. Mukherjee SP, Behar M, Birnbaum HA, Hoffmann A, Wright PE and Ghosh G. Structural analysis of the RelA:CBP/p300 interaction reveals its functional role in RelA-driven transcription. (2013) Plos Biol 11(9).
  4. Mohan PM, Mukherjee S, Chary KV. Differential native state ruggedness of the two Ca2+-binding domains in a Ca2+ sensor protein (2008) Proteins 70:1147-53.
  5. Mukherjee S, Mohan PM, Kuchroo, K, Chary KV. Energetics of Native Energy Landscape of a Two-domain Calcium Sensor Protein: Distinct Folding Features of the Two Domains. (2007) Biochemistry 46:9911-9.
  6. Mukherjee S, Mohan PM, and Chary KV. Magnesium promotes conformational switching action of a Calcium sensor protein. (2007) Biochemistry 46:3835-45
  7. Mukherjee S, Muralidhar D, Atreya HS, Szyperski T, Jeromin A, Sharma Y, Chary KV. Letter to the Editor: 1H, 13C and 15N resonance assignments for the myristoylated neuronal calcium sensor (NCS-1). (2006)  J.Biomol.NMR 36 Suppl 5:48
  8. Mustafi SM, Mukherjee S, Chary KV, Cavallaro G. Structural basis for the observed differential magnetic anisotropic tensorial values in calcium binding proteins. (2006) Proteins 65:656-69
  9. Mukherjee S, Fairwell T, Sharma Y, Chary KV. Importance of a single hydrophobic residue in calcium binding affinity to EF-hand peptides. (2006) Calcium Binding Proteins 1:115-19
  10. Mukherjee S, Kuchroo K, Chary KV. Structural characterization of the apo form of a calcium binding protein from Entamoeba histolytica by hydrogen exchange and its folding to the holo state. (2005) Biochemistry 44: 11636-45
  11. Mukherjee S, Mustafi SM, Atreya HS, Chary KV. Measurement of 1J(Ni, Cai), 1J(Ni, C’i-1), 2J(Ni, Cai-1), 2J(HNi, C’i-1) and 2J(HNi, Cai) values in 13C/15N labeled proteins. (2005) Magn Reson Chem. 43:326-329
  12. Mukherjee S, Mustafi SM, Sheth AA, Atreya HS, Chary KV. NMR of EF-hand calcium binding proteins. (2004) Proc Indian Natn Sci Acad, 70A: 615-25 (Review Article)
  13. Mustafi SM, Mukherjee S, Chary KV, Bianco CD, Luchinat C. Energetics and Mechanism of Ca2+ displacement by lanthanides in a calcium binding protein. (2004) Biochemistry 43: 9320-31
  14. Atreya HS, Mukherjee S, Chary KV, Lee YM, Luchinat C. Structural basis for sequential displacement of Ca2+ by Yb3+ in a protozoan EF-hand calcium binding protein. (2003) Protein Science 12:412-25