Soma Rohatgi - Department of Biosciences and Bioengineering,Indian Institute of Technology Roorkee
Soma Rohatgi
Soma Rohatgi Assistant professor soma.rohatgi@bt.iitr.ac.in 01332-284831 Website
Areas of Interest
  • Infectious Disease Immunology, Vaccine Development and Research, Antibody Therapeutics, Monoclonal Antibodies, Antibody Engineering, Molecular Biology and Immunogenetics, VDJ rearrangements at Single cell level, Antibody Repertoire studies, Immunomodulation, Clinical and Translational Immunology, Human case/control studies in the setting of Infectious Diseases (fungal and viral pathogens), Biomarker Analysis
Professional Background
FromPeriodPositionOrganisation
2010-01-014 years Postdoctoral Research FellowAlbert Einstein College of Medicine, New York
2009-01-011 year Postdoctoral Research FellowNational Institute on Aging, NIH, Maryland, USA
Educational Details
DegreeSubjectUniversityYear
PhDImmunologyNational Institute of Immunology, New Delhi2009
MScGeneticsUniversity of Delhi, South Campus2003
BSc (Hons)ZoologyUniversity of Delhi, North Campus2001
Sponsored Research Projects
TopicFunding AgencyStart DatePeriod
Role of B cells and Antibodies in Candida and Chikungunya virus infectionsDBT2015-01Ongoing
Vaccine Research against Non albicans Candida speciesDST SERB2017-01Ongoing
Research Scholar Groups
Scholar NameInterest
Manisha ShuklaImmunology
Pankaj ChandleyImmunology
Referred Journal Papers
  • Vaccination with Secreted Aspartyl Proteinase 2 Protein from Candida parapsilosis Can Enhance Survival of Mice during C. tropicalis-Mediated Systemic Candidiasis, 1. Manisha Shukla and Soma Rohatgi, The American Society of Microbiology (ASM Press), 2020 , Infection and immunity , 88 (10) vols , 00312-20 pages
  • Naïve B cells reduce fungal dissemination in Cryptococcus neoformans infected Rag1(-/-) mice, 2, Dufaud C, Rivera J, Rohatgi S, Pirofski LA., Taylor & Francis, 2018 , Virulence , 9 (1) vols , 173-184 pages
  • Antibody and B Cell Subset Perturbations in Human Immunodeficiency Virus-Uninfected Patients With Cryptococcosis, 3. Rohatgi S, Nakouzi A, Carreño LJ, Slosar-Cheah M, Kuniholm MH, Wang T, Pappas PG, Pirofski LA., Oxford Press, 2017 , Open Forum infectious Diseases , 5 (1) vols , ofx255 pages
  • Host immunity to Cryptococcus neoformans, 4. Rohatgi S, Pirofski LA., Future Medicine, 2015 , Future Microbiology , 10 (4) vols , 565-581 pages
  • Fc gamma receptor 3A polymorphism and risk for HIV-associated cryptococcal disease, 5, Rohatgi S, Gohil S, Kuniholm MH, Schultz H, Dufaud C, Armour KL, Badri S, Mailliard RB, Pirofski LA., American Society for Microbiology (ASM Press), 2013 , mBio , 4 (5) vols , e00573-13 pages
  • Molecular characterization of the early B cell response to pulmonary Cryptococcus neoformans infection, 6. Rohatgi S, Pirofski LA., The American Association of Immunologists (AAI), 2012 , The Journal of Immunology , 189 (12) vols , 5820-30 pages
  • Molecular dissection of antibody responses against pneumococcal surface protein A: evidence for diverse DH-less heavy chain gene usage and avidity maturation, 7. Rohatgi S, Dutta D, Tahir S, Sehgal D., The American Association of Immunologists (AAI), 2009 , The Journal of Immunology , 182 (9) vols , 5570-85 pages
  • Systematic design and testing of nested (RT-)PCR primers for specific amplification of mouse rearranged/expressed immunoglobulin variable region genes from small number of B cells, 8. Rohatgi S, Ganju P, Sehgal D., Elsevier, 2008 , The Journal of Immunological Methods , 339 (2) vols , 205-19 pages
  • Eliminating expression of erucic acid-encoding loci allows the identification of "hidden" QTL contributing to oil quality fractions and oil content in Brassica juncea (Indian mustard), 9. Jagannath A, Sodhi YS, Gupta V, Mukhopadhyay A, Arumugam N, Singh I, Rohatgi S, Burma PK, Pradhan AK, Pental D., Springer, 2011 , Theoretical & Applied Genetics , 122 (6) vols , 1091-103 pages
Refereed Journal Papers
  1. Rohatgi S, Nakouzi A, Carreño LJ, Slosar-Cheah M, Kuniholm MH, Wang T, Pappas PG, Pirofski LA. Antibody and B Cell Subset Perturbations in Human Immunodeficiency Virus-Uninfected Patients With Cryptococcosis. Open Forum Infect Dis. 2017 Nov 18;5(1):ofx255.

  2. Dufaud C, Rivera J, Rohatgi S, Pirofski LA. Naïve B cells reduce fungal dissemination in Cryptococcus neoformans infected Rag1-/- mice. Virulence. 2018 Jan 1;9(1):173-184.

  3. Rohatgi S and Pirofski L (2014). Host Immunity to Cryptococcus neoformans. Future Microbiology 2015;10(4):565-81

  4. Rohatgi S, Gohil S, Kuniholm M, Schultz H, Dufaud C, Armour K, Badri S, Mailliard R, and Pirofski L. (2013) Fc gamma receptor 3A Polymorphism and Risk for HIV-associated Cryptococcal Disease. mBio. 4 (5): e00573-13.

  5. Rohatgi S and Pirofski L (2012). Molecular characterization of the early B cell response to pulmonary Cryptococcus  neoformans infection. Journal of Immunology Dec 15, 189, 5820-5830

  6. Rohatgi S, Dutta D, Tahir S and Sehgal D (2009) Molecular dissection of antibody responses against pneumococcal surface protein A: Evidence for diverse 'DH-less' heavy chain gene usage and avidity maturation. Journal of Immunology 182: 5570-5585.

  7. Rohatgi S, Ganju P and Sehgal D (2008) Systematic design and testing of nested (RT-)PCR primers for specific amplification of mouse rearranged/expressed immunoglobulin variable region genes from small number of B cells. Journal of Immunological Methods, Dec 31; 339(2): page 205-219.

  8. Jagannath A, Sodhi YS, Gupta V, Mukhopadhyay A, Arumugam N, Sivaraman I, Rohatgi S, Burma PK, Pradhan AK and Pental D. (2011) Eliminating pleiotropic effects of erucic acid-encoding genes allows the identification of “hidden” loci contributing to oil quality and oil content in oilseed mustard (Brassica juncea) Theoretical & Applied Genetics. Apr; 122(6): 1091-103

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