Singh, R.P - Department of Biosciences and Bioengineering,Indian Institute of Technology Roorkee
Singh, R.P
R.P. Singh Professor r.singh@bt.iitr.ac.in 91-01332-285792
Areas of Interest
  • Microbial Biotechnology, Nanobiotechnology, Microbial Enzymes, Molecular Biology, Biofuels, Bioremediation, Drug Delivery Systems
Professional Background
FromPeriodPositionOrganisation
2011-01-01OngoingMember, Commitee on GMOFSSAI, Govt.of India
2006-01-018 years Member Task Force, DBT Govt. of India
2014-01-01OngoingMember Task Force, DRDO, Govt.of India
2006-01-01OngoingProfessor, IIT Roorkee
2001-01-012 years HeadDeptt of biotec,IIT Roorkee
2003-01-013 years Associate Professor, IIT Roorkee
Multiple Posts
FromPeriodPositionOrganisation
2004-01-012 years Officer in Charge, Security,IIT Roorkee
2006-01-016 years Prof. In-charge Guest HouseIIT Roorkee
2005-01-01Chief Staff AdvisorThomso
2004-01-012 years Chief WardenRavindra Bhawan
Educational Details
DegreeSubjectUniversityYear
Ph.DMicrobiologyCentral Drug Research Institute,Lucknow,India1983
M. Sc.BiochemistryG. B. Pant University of Ag. Technology, Pantnagar1979
Sponsored Research Projects
TopicFunding AgencyStart DatePeriod
Regulation of rpt-1: -------------IL-2r expressionCancer Research Institute, New York, USA1990-0130 years 7 months
Microbial Biosynthesis-------Armed Forces PersonnelDRDO, New Delhi1995-0125 years 7 months
Cell Surface ---------and FunctionDST, New Delhi1995-0125 years 7 months
Steroid 16a-------- molecular probeUGC, New Delhi1996-0124 years 7 months
Development of -----------Gluconic acidUPCST, Lucknow2002-0118 years 7 months
Bioprocess Development --------------------cheap carbohydrate AICTE, New Delhi2005-0115 years 7 months
Fund for Improvement---------------------- TechnologyDST, New Delhi2008-0112 years 7 months
Production of alkalophilic ----------------------------industriesDST, New Delhi2010-0110 years 7 months
Study of ----------------misfoldingDST, New Delhi2013-01Ongoing
Evaluation of ----------------Himalayan regionDRL, DRDO, Tezpur2013-017 years 7 months
Ganga River Basin Management Plan ProjectMinistry of Environment and Forest2012-018 years 7 months
De novo production----------Advanced BiofuelsBiocare DBT, New Delhi2014-016 years 7 months
Cloning and ------------------------------ Escherichia coli DBT, New Delhi2015-015 years 7 months
Development of Engineered Microalgae for Enhanced Lipid AccumulationDBT, New Delhi2015-01Ongoing
Memberships
  • Proc. Innov. Network, UK, Member
  • Fed. of European Microbiologists,, Member
  • Biotechnology Res. Soc. of India, Life Member
  • Soc. of Biol. Chemists, India, Life Member
  • Assoc. of Microbiologists of India, Life Member
  • Bioinformatics Soc. of India,, Life Member
  • New York Acad. of Sciences, , Member, 1996-97
Visits to outside institutions
Institute VisitedPurpose of VisitDate
UAMS, Little Rock, USAVisiting Assistant Prof.2020-08-04
Harvard Medical School, DFCI, Boston, USAResearch Fellow2020-08-04
Harvard Medical School, DFCI, Boston, USAPost Doctoral Fellow2020-08-04
NIH, Bethesda, USAVisiting Fellow2020-08-04
Refereed Journal Papers
  • Pareek N, Ghosh S., Singh R. P. and Vivekanand V. (2014). Enhanced production of chitin deacetylase by Penicillium oxalicum SAEM-51 through response surface optimization of fermentation conditions. 3 Biotech,  4(1): 33–39.
  • Pareek, N., Vivekanand and Singh R. P. (2013). Structural, molecular  and functional aspects of Chitin deacetylase, Advances in Enzyme  Biotechnol, P. Shukla, B.I. Pletschke eds., Springer Publ., 125-136.
  • Saroj S, Agarwal P, Dubey S and Singh R. P. (2013). Manganese Peroxidases: molecular diversity, heterologous expression and applications. Advances in Enzyme  Biotechnol, P. Shukla, B.I. Pletschke eds.Springer Publ., 67-87.
  • Saroj S, Agarwal P, Dubey S and Singh R. P. (2013). Manganese Peroxidases: molecular diversity, heterologous expression and applications. Advances in Enzyme  Biotechnol, P. Shukla, B.I. Pletschke eds.Springer Publ., 67-87.
  • Saroj  S and Singh R. P.( 2014 )  Microbial Degradation of Azo dyes: A Promising and An Ecofriendly Approach, In:  Biodegradation and Bioremediation ,Vol 11, M Ahmed and J N Govil eds Studium Press LLC, USA, 213-240.]
  • Agarwal P., Saroj S., Dubey S. and Singh R. P. (2014) L-Tyrosinase- A Multifunctional Enzyme: Structural and Molecular Features. In: Gene and Protein Engineering, Vol 5, J K Thakur and J N Govil eds Studium Press. LLC, USA, 425-446.
  • Dubey S., Saroj S., Agarwal P. and Singh R. P. (2014)  Bacterial Cellulose: An Innovative Nanobiopolymer for Drug Delivery. In : Nanobiomedicine  Vol 2 :Nanopharmaceuticals, B S Bhoop and J N Govil eds.  Studium Press, LLC  Houston, USA,. 185-200.
  •  Vashisth P , Kumar N, Pemmaraju S C, Pruthi  P A, Mallick V, Singh H, Patel A, Mishra N C, Singh R. P. and Pruthi V. (2013). Antibiofilm activity of quercetin capsulated cytocompatible nanofibers against Candida albicans, Journal of Bioactive and Compatible Polymers,  28 (6), 652-665.
  • Vashisth, P., Parul, A., Singh R. P. and Pruthi V. (2014). Process optimization for fabrication of gellan based electrospun  nanofibers. Carbohydrate Polymers 109, 16-21.
  • Patel, A., Pravez,M., Deeba,F., Pruthi,V., Singh R. P., Pruthi, P.A. (2014). Boosting accumulation of neutral lipids in Rhodosporidium kratochvilovae HIMPA1 grown on hemp (Cannabis sativa Linn) seed aqueous extract as feedstock for biodiesel production. Bioresource Technology, 165, 214-222.
  • Pareek, N., Ghosh, S., Singh R. P., Vivekanand, V. (2014). Mustard oil cake as an inexpensive support for production of chitin deacetylase by Penicillium oxalicum  SAEM-51 under solid-state fermentation. Biocatalysis and Agricultural Biotechnology, 3: 212-217.
  • Saroj S, Kumar K, Pareek N, Prasad R, Singh R. P. ( 2014 ). Biodegradation of azo dyes Acid Red 183, Direct Blue 15 and Direct Red 75 by the isolate Penicillium oxalicum SAR-3. Chemosphere 107, 240-248.
  • Saroj S., Kumar K.,  Prasad, M., Singh, R.P. (2014). Differential expression of peroxidase  and ABC transporter as the key regulatory components for degradation of azo dyes by P. oxalicum SAR-3. Functional & Integrative Genomics, 14 ( 4 ), 631-642.
  • Pareek, N., Ghosh, S., Singh, R.P. and Vivekaknand, V. ( 2014 ). Enhanced production of chitin decacetylase by Penicillium oxalicum SAEM-51 throgh response surface optimization of fermentation conditions. 3 Biotech, 4 ( 1 ), 33-39.
  • Patel, A;  Pruthi, V; Singh, R.  P., Pruthi, P.A. (2014). Synergistic effect of fermentable and non-fermentable carbon sources enhances TAG accumulation in oleaginous yeast Rhodosporidium kratochvilovae HIMPA1. Bioesource Technol., 188: 136–144.
  • Batra M., Sharma R., Chandra V., Aggarwal M., Agarwal U., Gupta P., Singh R P., and Tomar S. (2015). In silico and  proteomic analysis of protein methyltransferase CheR from Bacillus subtilis.   Intl J Biol Macromol, 77: 168-180.
  • Patel, A;  Sindhu, D.K., Arora, N., Singh, R. P., Pruthi, V., Pruthi, P. ( 2015 ). Biodiesel production from Non-edible Lignocellulosic biomass of Cassia fistula L. fruit pulp using oleaginous yeast Rhodosporidium  kratochvilovae HIMPA1 . Bioesource Technol., 197, 91-98.
  • Saroj, S., Dubey, S., Agrawal, P., Prasad, R. and Singh, R. P. ( 2015 ). Evaluation of the efficacy  of a fungal consortium for degradation of azo dyes and simulated textile dye effluents. Sustainable Water Resources Management, 1 : 233-243.
  • Vashisth, P., Singh R. P. and Pruthi V. (2015) A controlled release system for quercetin from biodegradable poly(lactide-co-glycolide)-polycaprolactone nanofibres and its in vitro anti tumor activity. Journal of Bioactive and Compatible Polymers, 31(3),1-13.
  • Agarwal P., Pareek N., Dubey S., Singh J. and Singh R. P. (2016). Aspergillus niger PA2:A Novel Strain for Extracellular Biotransformation of L-Tyrosine into L- DOPA, Amino Acids,  48 ( 5 ), 1253-1262.
  • Vashisth P, Srivastava AK, Nagar H, Raghuwanshi N, Sharan S, Nikhil K, Pruthi PA, Singh RP, Roy P, Pruthi V.( 2016 ). Drug functionalized microbial polysaccharide based nanofibers as transdermal substitute. Nanomedicine, 12(5):1375-85.
  • Vashisth P, Nikhil K, Roy P, Pruthi PA, Singh RP, Pruthi V. ( 2016 ) A novel gellan– PVA nanofibrous scaffold for skin tissue regeneration: Fabrication and characterization.Carbohydrate polymers. 2016; 136:851-859.
  • Agarwal, P., Dubey, S., Singh, M., Singh, R.P. et al. ( 2016 ). Aspergillus niger PA2 Tyrosinase covalently immobilized on a novel eco-friendly Bio-composite of chitosan-  gelatin and its evaluation for L-DOPA Production. Front in Microbiol. 7:1-10.
  • Agarwal P., Singh J., Singh R.P.( 2017 ). Molecular cloning and characteristic features of  a Novel Extracellular Tyrosinase from Aspergillus niger PA2. Appl. Biochem.Biotechnol 182 (1), 1-15.
  • Dubey S., Sharma R. K., Agarwal P., Singh J., Sinha N. and Singh R. P. (2017). From rotten grapes to industrial exploitation: Komagataeibacter europaeus SGP37, a micro- factory for macroscale production of bacterial nanocellulose. International Journal of Biological Macromolecules, 96, 52–60.
  • Mondal P, Kumari P, Singh J, Verma S, Chaurasia A K, and Singh R. P. ( 2017 ). Oil from Algae : In Sustainable Utilization of Natural Resources, P. Mondal and A K  Dalai eds. CRC Press. Taylor and Francis, USA.213-253.
  • Singh, J., Dubey, S. and Singh, R. P. (2017). Lipidomic Profiling: A new approach unravelling the polar and neutral lipids in Scenedesmus abundans and Chlorella sp. under  nitrogen limited conditions.Journal of Bioremediation & Biodegradation,8 ( 5 ) : 37, 2017.
  •  Vashisth, Raghuvanshi N, Nagar H, Srivastava A K, Singh R P,  Pruthi V.( 2017 ).Ofloxacin loaded gellan/PVA nanofibers - synthesis, characterization and evaluation of their gastroretentive/ mucoadhesive drug delivery potential.  Materials Science and Engineering: C. 71(1),611–619.
  • Dubey S., Singh J. and Singh R. P. (2018 ). Biotransformation of sweet lime pulp waste into high- quality nanocellulose with an excellent productivity using Komagataeibacter europaeusSGP37 under static intermittent fed-batch cultivation, Bioresource Technol. 247, 73-80.




                                                      
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