Naveen Kumar Navani
Naveen Kumar Navani
Professor
naveen.navani@bt.iitr.ac.in
+91 1332 285677
Areas of Interest
- Molecular Biology, Synthetic Biology, Gene regulation, Microbial Biotechnology and Nanobiotechnology, Aptamers and MEMS nanodevices in Diagnostics, Probiotic recombinant enzymes, NanoBiotic Materials
- Microbes' mediated bioremediation of polluted environments., Isolation and characterization of microbes from extreme and polluted environments.
Professional Background
| From | To | Designation | Organisation |
|---|---|---|---|
| 1996 | 2003 | Scientist | National Bureau of Animal Genetic Resources (ICAR) |
Honors and Awards
| Award | Institute | Year |
|---|---|---|
| Fellow of National Academy of Dairy Science | NATIONAL ACADEMY OF DAIRY SCIENCES | 2019 |
| Young Innovator Award | Uttarakhand Council for Science and Technology | 2010 |
Educational Details
| Degree | Subject | University | Year |
|---|---|---|---|
| Post-Doctoral Research | Functional Nucleic acids/Molecular Biology | McMaster University, Hamilton, Canada | 2007 |
| Ph.D. | Biotechnology/Molecular Biology | Institute of Microbial Technology (CSIR), Chandigarh | 2002 |
| M.Sc. | Biotechnology | National Dairy Research Institute, Karnal | 1993 |
Administrative Background
| From | To | Designation | Organisation | Level |
|---|---|---|---|---|
| 2014 | 2017 | Associate Dean of student Welfare | Indian Institute of Technology Roorkee | |
| 2009 | 2013 | Warden, Azad Bhawan | Indian Institute of Technology Roorkee |
Sponsored Research Projects
| Topic | Funding Agency | Year |
|---|---|---|
| Development of ready to go culture strips for fermented dairy products | BIRAC | 2019 |
| Mitigation of food borne pathogens using combination of natural food grade peptides decorated on nan | MHRD-STARS | 2019 |
| A field survey of ethnic fermented food beverages of Uttarakhand | UCOST | 2019 |
| Development of Nanoparticle based Aptasensor for detection of bacterial pathogens and xenobiotics in | DBT | 2017 |
| Detection and Control of Bacterial Pathogens in Poultry by Developing Chemical Genomic Strategies to | NASF-ICAR | 2017 |
| Application of probiotic bacteria for enhancing nutritional status of underutilised millets of Uttar | UCOST | 2017 |
| Development of Nucleic acid aptamer based functional nanodevice strategies for sensing, capture and | DST Nanomisssion | 2016 |
| Value addition to the hill cattle of Uttarakhand using biotechnological investigation | UCOST | 2015 |
| Development of an Aptamer Biosensing system for Detection of water-borne Pathogen E.coli O157:H7 | DBT, Govt of India | 2012 |
| Detection and Mitigation of Dairy Pathogens and Detection of Adulterants using Chemical Biology | Indian Council of Agricultural Research (ICAR), NAIP | 2009 |
Memberships
- American Society of Microbiology (ASM), Member
- ADNAT (Association for promotion of DNA fingerprinting and other DNA technologies), Joint Secretary
Projects and Thesis Supervised
| Title of Project | Names of Students |
|---|---|
| Molecular investigations and applications of selected GRAS molecules for antibacterial and anticance | Tamoghna Ghosh |
| Synthesis and multifunctional application of biomolecule mediated Ag-Fe2O3 nanohybrids | Mandeep Kaloti |
| Molecular and Biochemical studies of probiotic properties of Lactobacillus fermentum NKN51 | Rekha Sharma |
| Aptamers for adulterant detection and Nano-based strategies for pathogen control | Lambadi Paramesh Ramulu |
| Development of a promoter based bacterial reporter system for a sensing stress response | Santosh Kumar Srivastava |
| Generation of DNA aptamers for detection of Escherichia coli and Salmonella enterica | Tarun Kumar Sharma |
| Screening and characterization of an extracellular protease from halophilic bacterium | Meenu Gupta |
Research Scholar Groups
| Scholar Name | Interest |
|---|---|
| Tamoghna Ghosh | Metabolic engineering, combinatorial gene engineering |
| Shahnawaz A. Baba | Development of functional nucleic acid based sensors for detection of biological species |
| Santosh Kumar Srivastava | Antisense RNA expression in prokaryotes |
| Shubham Jain | Aptamers |
| Rekha Sharma | Probiotics |
| Ajmal Hussain | Probiotics |
| Paramesh Lambadi | Aptasensors for small molecules and pathogens |
| Ankita Bhatt | Whole Cell Biosensor |
| Mandeep Kaloti | Synthesis of composite magnetic nanomaterials and their biotechnological applications |
| Tarun Kumar Sharma | In Vitro Evolution and Aptamer Generation |
| Rajat Dhyani | Whole Cell Biosensors and Chemical Genetics |
| Pardeep Soni | NanoSensors and Bioremediation |
| Anupama Semwal | Probiotics and Value addition to Millets |
PHDs Supervised
| Topic | Scholar Name | Status of PHD | Registration Year |
|---|---|---|---|
| Molecular investigations and applications of selected GRAS molecules for antibacterial and anticance | Tamoghna Ghosh | A | 2012 |
| Development of functional nucleic acid based sensors for detection of biological species | Shahnawaz A Baba | O | 2014 |
| Development of gluten free probiotics food and methods for food pathogen detection | Anupama Semwal | O | 2015 |
| Synthesis and multifunctional application of biomolecule mediated A-Fe2O3 nanohybrids | Mandeep Kaloti | A | 2014 |
| Nanomaterials based biosensors for the detection of Pathogens and small molecules | Pardeep Kumar | O | 2013 |
| Development of recombinant whole cell biosensors | Rajat Dhyani | O | 2014 |
| Screening and characterization of an extracellular protease from halophilic bacterium | Meenu Gupta | A | 2010 |
| Molecular and Biochemical studies of probiotic properties of Lactobacillus fermentum NKN51 | Rekha Sharma | A | 2010 |
| Diagnostics platform development using DNA aptamers | Shubham Jain | O | 2017 |
| Aptamers for adulterant detection and Nano-based strategies for pathogen control | Lambadi Paramesh Ramulu | A | 2008 |
| Carbon nanotube based devices for sensor applications | Narender Kumar | O | 2013 |
| Development of a promoter based bacterial reporter system for a sensing stress response | Santosh Kumar Srivastava | A | 2007 |
| Generation of DNA aptamers for detection of Escherichia coli and Salmonella enterica | Tarun Kumar Sharma | A | 2007 |
Courses or Conferences Organised
| Conference Name | Sponsored By | Date |
|---|---|---|
| AROHP-2019, Antibiotic Resistance- One health propective | ADNAT | 05-03-2019 |
Special Lectures Delivered
| Title | Place | Date |
|---|---|---|
| Transcriptional responsive Whole-cell Bacterial Biosensors for applications in Metabolic engineering | Association of Microbiologist of India (AMI)Mahendergarh, Haryana | 15-11-2019 |
| Fermented dairy foods and their health benefits | ICAR-NDRI Karnal | 25-05-2018 |
| Bioengineering Approaches for Selection of Synthetic Functional Nucleic Acids | CSIR-CCMB | 2018 |
| Innovative Biotechnological Approaches for Improving Animal Health and Productivity | ICAR-NRC Mithun | 2018 |
| DNA finger printing and associated DNA technologies | IIT Guwahati | 27-01-2018 |
| Molecular insights in to the Probiotic effects of Lactobacilli for creation of New Generation Dairy | SVVU, Tirupati | 2018 |
Books Authored
Edited Book series on Nanotechnology (1-10 Volumes). (2013); Studium press LLC, USA.
- Vol.1: Fundamentals and Applications – Naveen Kumar Navani, Shishir Sinha and JN Govi
- Vol.2: Synthesis and Characterization- Shishir Sinha , Naveen Kumar Navani and JN Govil
- Vol.3: Properties of Nanomaterials - Shishir Sinha , Naveen Kumar Navani and JN Govil
- Vol.4: Nanomaterials and Nanostructures- Naveen Kumar Navani, Shishir Sinha and JN Govil
- Vol.5: Defence Applications Nanotechnology - Naveen Kumar Navani, Shishir Sinha and JN Govil
- Vol.6: Nanotechnology;Energy and Environment- Shishir Sinha , Naveen Kumar Navani and JN Govil
- Vol.7: Nanotechnology;Diagnostics and Therapeutics -- Naveen Kumar Navani, Shishir Sinha and JN Govil
- Vol.8: Nanotechnology;Electronics and Photovoltaics- Shishir Sinha , Naveen Kumar Navani and JN Govil
- Vol.9: Nanotechnology;Civil/ Construction Engineering- Shishir Sinha , Naveen Kumar Navani and JN Govil
- Vol.10: Nanosensing-- Naveen Kumar Navani, Shishir Sinha and JN Govil
Book Chapters contributed -
- Naveen Kumar Navani, Casey Fowler and Yingfu Li (2009) Aptamers for the biosensing of Pathogens. Book Chapter in Biosensors, Microsystems and the Recognition elements Edited by M. Zourob and APF Turner-Cambridge University, UK.
- Naveen Kumar Navani, Wendy Mok and Yingfu Li (2009) Aptamer Ligands as sensors for proteins and small molecules. Methods in Biotechnology,” Humana Press, USA.
- B. Prakash, N.K. Navani and P.K. Jain (2000) Cytogenetic, blood groups and biochemical polymorphism and molecular genetic characterization of Indian farm animal genetic resources. in “Systems approach to animal farming” eds. R. Nagarcenkar & R.R. Lokeshwar.
- Naveen Kumar Navani, Pradeep Jain and Rajendra Sahai (2001) DNA technology and its role in biodiversity conservation . in “Current Topics in Environment Biology” Eds. G.Tripathi & G.C. Pandey, pp. 501-514, ABD Publishers(India).
- Naveen Kumar Navani, Rekha Sharma, Bharani Kumar, S.P.S. Ahlawat and Dinesh Pandey -Exploitation of microbial diversity for bioremediation using genetic tools – book chapter in Biotechnology in Environmental Management - edited by T.K. Ghosh, T. Chakrabarti and G. Tripathi. New Delhi, A.P.H. Pub., 2005, 2 Vols., xxxiv, 715 p
Refereed Journal Papers
- Chakarborthy P., Deepankar P., Dash PS., Priya., Srivastva S, Dhayani R., Navani N.K., Sharma D., Sarangi P "Electrostatic Surface Potential of Macrophages Correlates With Their Functional Phenotype" Accepted for publication in Inflammation journal. (Impact factor: 2.9)
- Bhando, T., Bhattacharyya, T., Gaurav, A., Akhter, J., Saini, M., Gupta, V. K.,Navani N.K... & Biswas, D.Chaudhary R., Pathania R.(2019). Antibacterial properties and in vivo efficacy of a novel nitrofuran, IITR06144, against MDR pathogens. Journal of Antimicrobial Chemotherapy. (Impact factor: 5.2)
- Dalal, U., Gupta, V. K., Reddy, S. N., & Navani, N. K. (2019). Eradication of Water Borne Pathogens Using Novel Green Nano Ag-Biocomposite of Citrus Limetta Peels. Journal of Environmental Chemical Engineering, 103534. (Impact factor:1.19)
- T Ghosh, Beniwal, A., Semwal, A., & Navani, N. K. (2019). Mechanistic Insights Into Probiotic Properties of Lactic Acid Bacteria Associated With Ethnic Fermented Dairy Products. Frontiers in Microbiology, 10, 502. (Impact factor:4.2)
- Verma, A., Ghosh, T., Bhushan, B., Packirisamy, G., Navani, N. K., Sarangi, P. P., & Ambatipudi, K. (2019). Characterization of difference in structure and function of fresh and mastitic bovine milk fat globules. PloS one, 14(8), e0221830 (Impact Factor: 2.77)
- T Ghosh, Srivastava, S.K., Gaurav, A., Kumar, A., Kumar, P., Yadav, A.S.,& Navani, N. K. (2019). A combination of linalool, vitamin C, and copper synergistically triggers reactive oxygen species and DNA damage and inhibits Salmonella enteric subsp. enterica serovar Typhi and Vibrio fluvialis. Applied and Environmental Microbiology. 85(4), e02487-18. (Impact factor: 4.0)
- Kumar, N., Navani, N. K., & Manhas, S. K. (2019). Altering the Schottky Barrier Height and Conductance by Using Metal Nanoparticles in Carbon Nanotubes-Based Devices. IEEE Transactions on Electron Devices, 66(6), 2789-2794. (Impact factor: 2.62).
- R Sharma, P Kumar, V Kaushal, R Das, Naveen K. Navani (2018) A novel protein tyrosine phosphatase like phytase from Lactobacillus fermentum NKN51: Cloning, characterization and application in mineral release for food technology applications. Bioresource Technology 249:1000-1008. (Impact factor: 6.6)
- SK Srivastava, VR Iyer, T Ghosh, PR Lambadi, R Pathania, Naveen K. Navani (2016) Isolation of a non-genomic origin fluoroquinolones responsive regulatory element using a combinatorial bioengineering approach. Nucleic Acids Research. 44(5):2451-61. (Impact factor: 11.1)
- S Chamoli, P Kumar, Naveen K. Navani, AK Verma (2016) Secretory expression, characterization and docking study of glucose-tolerant β-glucosidase from B. subtilis. International journal of biological macromolecules. 85: 425-433. (Impact factor: 3.67)
- P Kumar, P Kumar, S Manhas, Naveen K. Navani (2016) A simple method for detection of anionic detergents in milk using unmodified gold nanoparticles. Sensors and Actuators B: Chemical. 233:157-161. (Impact factor: 6.3)
- M Kaloti, A Kumar, Naveen K. Navani (2015) Synthesis of glucose-mediated Ag–γ-Fe2O3 multifunctional nano-composites in aqueous medium – a kinetic analysis of their catalytic activity for 4-nitrophenol reduction. Green Chemistry. 17: 4786-99. (Impact factor: 9.12)
- P Kumar, PR Lambadi, Naveen K. Navani (2015) Non-enzymatic detection of ureausing unmodified gold nanoparticles based aptasensor. Biosensors and Bioelectronics. 72:340-7. (Impact factor: 9.5)
- M Gupta, S Mathur, TK Sharma, M Rana, A Gairola, Naveen K. Navani, R Pathania. (2015) A study on metabolic prowess of Pseudomonas sp. RPT 52 to degrade imidacloprid, endosulfan and coragen. Journal of Hazard Materials. 301:250-8. (Impact factor: 7.6)
- Supriya D. Patil, R.Sharma, T. Bhattacharyya, P. Kumar, M. Gupta, Bhupinder S. Chaddha, Naveen K. Navani, R. Pathania (2015). Antibacterial potential of a small peptide from Bacillus sp. RPT-0001 and its capping for green synthesis of silver nanoparticles. Journal of Microbiology. 53(9): 643-652. (Impact factor: 1.92)
- M Gupta, S Aggarwal, Naveen K. Navani, B Choudhury (2015) Isolation and characterization of a protease-producing novel haloalkaliphilic bacterium Halobiforma sp. strain BNMIITR from Sambhar Lake in Rajasthan, India. Annals of microbiology. 65(2): 677-686. (Impact factor: 1.12)
- PR Lambadi, TK Sharma, P Kumar, P Vasnani, ST Mouli, N Bisht, R Pathania, Naveen K. Navani (2014) Facile bio-functionalization of silver nanoparticles for enhanced antibacterial properties, endotoxin removal and biofilm control. International Journal of Nano medicine. 10:2155. (Impact factor: 4.30)
- SK Srivastava, PR Lambadi, T Ghosh, R Pathania, Naveen K. Navani (2014) Genetic regulation of spy gene expression in Escherichia coli in the presence of protein unfolding agent ethanol. Gene 548(1): 142-148. (Impact factor: 2.41)
- P Devi, SD Patil, P Jeevandham, , Naveen K Navani., ML Singla (2014) Synthesis, characterization and bactericidal activity of silica/silver core-shell nanoparticles. Journal of material Science: Material Medical. DOI 10.1007/ss10856-014-5265-9. (Impact factor: 2.32)
- R Sharma, S Arya, SD Patil, A Sharma, PK Jain, Naveen K Navani, R Pathania (2014) Identification of novel regulatory small RNAs in Acinetobacter baumannii. PLoS One 9(4): e93833. (Impact factor: 2.80)
- IN Ghosh, SD Patil, TK Sharma, SK Srivastava, R Pathania, Naveen K Navani (2013) Synergistic action of cinnamaldehyde with silver nanoparticles against spore-forming bacteria: a case for judicious use of silver nanoparticles for antibacterial applications. International Journal of Nanomedicine. 8: 4721-31. doi: 10.2147/IJN.S49649. Epub 2013 Dec 10. (Impact factor: 4.30).
- SD Patil, R Sharma, S Srivastava, Naveen K Navani, R Pathania (2013) Down regulation of yidCin Escherichia coli by antisense RNA expression results in sensitization to antibacterial essential oils eugenol and carvacrol. PLoS One 8 (3): e57370. (Impact factor: 2.80)
- WW Mok, Naveen K. Navani, C Barker, BL Sawchyn, J Gu. R Pathania, RD Zhu, ED Brown, Y Li (2009) Identification of a toxic peptide through bidirectional expression of small RNAs. Chembiochem. 10(2):238-41. (Impact factor: 2.84)
- Naveen K Navani, WK. Mok, Y Li (2008) Aptamer Ligands as sensors for proteins and small molecules. Methods in Biotechnology. 399-415. Humana Press, USA. A Allali- Hassani, MP Pereira, , ED Brown, Y Li (2007) Isolation of DNA aptamers for CDP-ribitol synthase, and characterization of their inhibitory and structural properties. Chembiochem. 8(17):2052-2057. (Impact factor: 2.84)
- A Craney, T Hohenauer, Y Xu, Naveen K Navani, Y Li, J Nodwell (2007) A synthetic lux CDABE gene cluster optimized for expression in high-GC bacteria. Nucleic Acids Research. 35(6):e46. (Impact factor: 11.2)
Patents Filed:
- Naveen Kumar Navani, Ranjana Pathania, Tarun K Sharma, Aradhana Chopra, Manish Rana. CRN019 Development of an aptamer-gold nanoparticles based rapid and sensitive detection system for Salmonella enteric serovarTyphi. Number 907/DEL/2014.
- Ranjana Pathania, Naveen K Navani, Atin Sharma, Rajnikant Sharma, Abin Ghosh. Nucleotide sequences specific for detection of Acinetobacter baumannii. Number 906/DEL/2014.
- Naveen Kumar Navani, Ranjana Pathania, Tarun K Sharma, MahakSapraCRN018 A system and method of a colorimetric sensor for ureadetection. Number 900/DEL/2014. Dated 28.03.2014.
- Naveen Kumar Navani, PiyushKalra, Paramesh R Lambadi. CRN020 - A nucleotide sequence based colorimetric nanosensor for detection of urea. Number 901 /DEL/2014. dated28.03.2014
- Naveen Kumar Navani, Tamoghna Ghosh. Asparaginase and its variants – Number: 201811019299 - May 23,2018.
- Naveen Kumar Navani, Shahnawaz Ahmad Baba, Piyush Kumar. Single stranded nucleotide sequence specific for binding to Acinetobacter baumannii and uses thereof – Submitted, being filed byBCIL
- Naveen Kumar Navani, AnupamaSemwal and ArunBeniwal. Composition and method for development a probiotics edible film and uses thereof- Submitted, being filed byBCIL