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Debabrata Sircar
Debabrata Sircar Assistant Professor debsrfbt[at] (91)-1332 285540
Areas of Interest
  • ROSomics, The use of genetics and genomics resources for the improvement of fruit quality of Rosaceous plant
  • Metabolic Pathway Engineering, Elucidation & engineering of secondary metabolic pathways in selected medicinal plants
Professional Background
20112013Post-doctoral FellowIPB, TU-Braunschweig, GERMANY
20102011Post-doctoral FellowUniversity of Evora, PORTUGAL
Honors and Awards
University first in B.Sc BotanyVinoba Bhave University2001
DAAD Research Stays for University Academics and Scientists IIT Roorkee2015
University First, gold medal in M.Sc BotanyThe University of Burdwan, West Bengal2004
DAAD FellowshipInstitute for Pharmaceutical Biology, TU-Braunschweig, GERMANY2008
FCT Post-doctoral felloship (with evaluation score 5/5))Laboratory of molecular biology, University of Evora; PORTUGAL2010
Post-doctoral fellowshipInstitute for Pharmaceutical Biology, TU-Braunschweig, GERMANY2011-13
Educational Details
Ph.D.Plant BiologyIndian Institute of Technology Kharagpur2009
FCT, Post-doctoral fellowMolecular Plant Breeding researchUniversity of Evora, Portugal2010-2011
Post-doctoral fellowFunctional Genomics and Metabolomics researchInstitute for Pharmaceutical Biology, TU-Braunschweig, GERMANY2011-2013
Administrative Background
2015Till dateMember Secretary IBCInstitutional Biosafety Committee
2015Till DateOfficer In-Charge AdministrationBiotechnology Department IIT Roorkee
2014Till DateOfficer In-Charge Store & PurchaseBiotechnology Department IIT Roorkee
2014Till DateMember DRC (Departmental Research Committee)Biotechnology Department IIT Roorkee
Sponsored Research Projects
TopicFunding AgencyYear
Functional Genomics of phytoalexin Biosynthesis in appleSERB Fast Track2014
Research Scholar Groups
Scholar NameInterest
Mr. Shashank Sagar SainiMolecular analyses of phytoalexin biosynthesis in Pear
Mr. Amol SarkateFunctional Genomics of phytoalexin biosynthesis in apple
Ms. Deepa TeotiaMolecular analyses of Benzoic acid biosynthesis in Malus. domestica
Ms. Kriti JunejaMetabolomics in Phytomedicine
Courses or Conferences Organised
Conference NameSponsored ByDate
Molecular Signaling: Recent Trends in Biomedical and Translational Research’ (ICMS: RTBTR-2014)All Government and Private Funding agenciesDec 2014
National International Collaboration
Metabolomics and Functional Genomics of Rosaceous Plants.TU-BS-GermanyRP
Sub-cellular Localization of phytolaexin biosynthesis proteins in RosaceaeInstitute of Plant Biology, TU-BS, GermanyRP
Alternative oxidase gene as functional marker candidate metabolic re-programming.University of Evora, PORTUGALRP
Health protective Phytomedicine from selected Indian medicinal plantsIIT KharagpurRP
Molecular breeding in apple and pearICAR-CITH, SrinagarRP
Metabolic flux analyses in natural product BiosynthesisIIT MandiRP
Refereed Journal Papers

13.Teotoa D, Saini SS, Gaid M, Beuerle T, Beerhues L, Sircar D (2016) Development and Validation of a New HPLC Method for the Determination of Biphenyl and Dibenzofuran Phytoalexins in Rosaceae. J Chromatogr Sci (2016) doi: 10.1093/chromsci /bmw019.

12. Sircar D, Gaid M, Chizzali C, Reckwell D, Kaufholdt D, Beuerle T, Broggini GA, Flachowsky H, Liu B, Haensch R, Beerhues L (2015). Biphenyl 4-Hydroxylases Involved in Aucuparin Biosynthesis in Rowan and Apple are CYP736A Proteins. Plant Physiol. 168: 428-442 (Impact factor 7.8).

11. Gaid MM#, Sircar D#, Müller A, Beuerle T, Liu B, Ernst L, Hänsch R, Beerhues L (2012): Cinnamate:CoA ligase initiates the biosynthesis of a benzoate-derived xanthone phytoalexin in Hypericum calycinum cell cultures. Plant Physiol 160: 1267-80; (IF =7.8);[# - joint first author].

10. Moon UR, Sircar D, Barthwal R, Sen SK, Beuerle T, Beerhues L, Mitra A (2015). Shoot cultures of Hoppea fastigiata (Griseb.) C.B. Clarke as potential source of neuroprotective xanthones. J Nat Med DOI 10.1007/s11418-015-0904-x (Impact factor 1.5).

09.Santos-Mecedo E#, Sircar D#, Cardoso H, Peixe A, Arnholdt-Schmitt B (2012): Involvement of alternative oxidase (AOX) in adventitious rooting of Olea europaea L. microshoots is linked to adaptive phenylpropanoid and lignin metabolism. Plant Cell Rep. 31: 1581-90; (IF = 2.87) [[# - joint first author].

08. Sircar D, Cardoso HG, Mukherjee C, Mitra A, Arnholdt-Schmidt B (2012): Alternative oxidase (AOX) and phenolic metabolism in methyl-jasmonate-treated hairy root cultures of Daucus carota L. J. Plant Physiol 169: 657-663. (IF = 2.79) r:blue'># - joint first author].

07. Sircar, D., Mukherjee, C., Beuerle, T., Beerhues, L. and Mitra A. (2011): Characterization of p-hydroxybenzaldehyde dehydrogenase - the final enzyme of p-hydroxybenzoic acid biosynthesis in hairy roots of Daucus carota. Acta Physiol Plantarum 33:2019-2024. (IF = 1.23).

06. Sircar, D. and Mitra A. (2009): Accumulation of p-hydroxybenzoic acid in hairy roots of Daucus carota 2.Confirming biosynthetic steps through feeding of inhibitors and precursors. J. Plant Physiol. 166, 1370-1380. (IF = 2.79).

05. Gaid, MM.,# Sircar, D.,# Beuerle, T., Mitra, A. and Beerhues, L. (2009): Benzaldehyde dehydrogenase from chitosan-treated Sorbus aucuparia cell cultures. J. Plant Physiol. 166, 1343-1349. (IF = 2.79) [# - joint first author].

04. Chakraborty, D.,# Sircar, D.# and Mitra A. (2008): Phenylalanine ammonia-lyase-mediated biosynthesis of 2-hydroxy-4-methoxybenzaldehyde in roots of Hemidesmus indicus. J. Plant Physiol.  165, 1033-1040. (IF = 2.79) [#- joint first author].

03. Sircar, D. and Mitra, A. (2008): Evidence for p-hydroxybenzoate formation involving enzymatic phenylpropanoid side-chain cleavage in hairy roots of Daucus carota. J. Plant Physiol. 165, 407-414. (IF = 2.79).

02. Sircar, D., Dey, G. and Mitra A. (2007): A validated HPLC method for simultaneous determination of 2-hydroxy-4-methoxybenzaldehyde and 2-hydroxy-4-methoxybenzoic acid in root organs of Hemidesmus indicus. Chromatographia. 65, 349-353. (IF= 1.09).

01. Sircar, D., Roychowdhury, A. and Mitra, A. (2007): Accumulation of p-hydroxybenzoic acid in hairy roots of Daucus carota. J. Plant Physiol.  164, 1358-1366.  (IF = 2.79).