Pranita P. Sarangi - Department of Biosciences and Bioengineering,Indian Institute of Technology Roorkee
Pranita P. Sarangi
Pranita P. Sarangi Associate professor pranita.sarangi@bt.iitr.ac.in +91-1332-284788 Website
Areas of Interest
  • Cellular and Molecular Immunology, Immunopathology of infectious and inflammatory diseases, Immunooncology, Cancer Immunoediting, Immunomodulatory therapeutics, Systems Immunology
Professional Background
FromPeriodPositionOrganisation
2011-01-012 years Research FellowNational Institutes of Health/NIDCR, USA
2008-01-013 years Postdoctoral Research AssociateSchool of Medicine and Dentistry, University of Rochester, USA
2013-01-014 years Special Research VolunteerNational Institute of Health/NIDCR
2003-01-015 years Research AssistantUniversity of Tennessee, Knoxville, USA
2003-01-01Junior Veterinary OfficerDept of Fisheries and Animal Husbandry, Govt of Odisha
2002-01-011 year Veterinary Extension OfficerHeifer International/India
Multiple Posts
FromPeriodPositionOrganisation
2020-08-10OngoingAssociate ProfessorIIT Roorkee
2014-01-016 years 7 months Assistant ProfessorIIT Roorkee
2021-05-20OngoingNodal Officer: DST-Gender Advancement for Transforming Institutions (GATI)IIT Roorkee
2020-01-01OngoingNodal Officer- DST Vigyan Jyoti ShemeIIT Roorkee
2017-01-01OngoingMember, Institute Animal Ethics CommitteeIIT Roorkee
2016-01-01OngoingMember, Dept Academic Program Committee (PG Course Coordinator)IIT Roorkee
2017-01-013 years Faculty Advisor, NCC and NSSIIT Roorkee
2014-01-01OngoingIn Charge - Experimental Animal FacilityIIT Roorkee
2015-01-01OngoingAssociate NCC Officer3 UK CTR NCC, IITRoorkee
Honors and Awards
AwardInstituteYear
Featured in the eBook: WiSTEM, Nurture and Celebrate Women in STEMConfederation of Indian Industry (CII)2021
International Travel Support for FOCIS 2019DST-SERB2019
Early Career Faculty Travel Grant American Association of Immunologists2017
Innovative Young Biotechnologist Award (IYBA-2017) Department of Biotechnology, Govt of India2017
Best Oral presentation, Immunocon-2014Indian Immunology Society2014
Early investigator Travel Grant AwardShock Society2010
Travel Award for best oral presentationUniversity of Tennessee, Knoxville, USA2007
NIAID Biodefense Fellowship Keystone Symposium, Viral Immununity2006
Research Assistantship for Doctoral StudiesUniversity of Tennessee, Knoxville, USA2008
University Merit ScholarshipOdisha University of Agril. and Tech.2001
Educational Details
DegreeSubjectUniversityYear
PhDComparative and Experimental MedicineUniversity of Tennessee, Knoxville, USA2008
Bachelor in Veterinary Science Veterinary ScienceO.U.A.T, Bhubaneswar, India2002
Sponsored Research Projects
TopicFunding AgencyStart DatePeriod
Role of Fibulin7 in the modulation of T cell functionSRIC-IITR2014-053 years
Investigating the effects of yoga and meditation in combating anxieties and stress-induced immunosuppressionDST-SATYAM2021-02-251 year
Cell-matrix interraction in inflammationDBT-Biocare, Govt. of India2014-07-303 years
Immunomodulatory effect of adhesion protein Fibulin7 (Fbln7)SERB, Govt. of India2015-11-273 years
Immunoediting and Tumor associated macrophagesDBT, Govt. of India2018-05-033 years
Integrin signalling in Innate Immune cell migration and function in sepsisSERB, Govt of India2021-02-063 years
Memberships
  • American Association of Immunologists, Member
  • Federation of Clinical Immunology Societies, Member
  • Indian Association of Immunologists, Life Member
  • Odisha Veterinary Association, Life Member
Teaching Engagements
TitleCourse CodeClass NameSemester
ImmunotechnologyBTN-207B Tech Autumn
Vaccine TechnologyBTN-449B Tech Spring
Microbiology and BiochemistryBTN-651MTechAutumn
Immunology and ImmunotechnologyBTN-522MScSpring
PHDs Supervised
TopicScholar NameStatus of PHDRegistration Date
Extracellular Matrix Protein Remodelling During InflammationChandra BhanA2014-01-01
Role of Adhesion Protein Fibulin7 in modulation of macrophage functionsPapiya ChakrabortyA2014-01-01
Role of GTPases in immune cell migration and functionPankaj DipankarO2015-01
Immune cell trafficking in inflammationSiba Prasad DashO2016-01
Modulation of immune cell function by matrikinesNibedita DalpatiO2018-01
Systems immunology and immunoinformaticsPuneet KumarO2019-01
Cancer related inflammation Saloni GuptaO2019-01
Participation in short term courses
Couse NameSponsored ByDate
Systems ImmunologyFOCIS, USA2020-08
Books Authored
  1. Sarangi PP, Rouse BT. Herpetic Keratitis. 2009. Levin and Albert Ocular Disease: Mechanisms and Management, Chapter 12, Elsevier, 
  2. Bhan C, Dipankar P, Dash SP, Chakraborty P, Dalpati N, *Sarangi PP. 2020. . Biotechnological Advances for Microbiology, Molecular Biology, and Nanotechnology: Chapter 13. Recent Advances in imaging and Analysis of Cellular Dynamics in Real Time. An Interdisciplinary Approach to the Life Sciences. Apple Academic Press.

 

Refereed Journal Papers

2021

1.   Dash SP, Dipankar P, Burange PS, *Rouse BT, *Sarangi PP. Climate Change: how it impacts the emergence, transmission, resistance and consequences Viral Infections in animals and plants. Critical Reviews in Microbiology. 2021 Feb 11: 1-16 

2.     Dipankar P, Kumar P, Dash SP, *Sarangi PP. Functional and Therapeutic Relevance of Rho GTPases in Innate Immune Cell Migration and Function During Inflammation: An In-silico perspective. (Mediators of Inflammation. 2021 Feb 13 (Special Issue-Invited Review)

 

2020

3.   Chakraborty P,  Dash, SP, Dalpati N, Kumar P, Jain D, *Sarangi PP. A C-terminal Fragment of Adhesion Protein Fibulin-7 Inhibits  Growth of Murine Breast Tumor by Regulating macrophage reprogramming. The FEBS Journal. 16th April 2020. (Highlighted in a commentary in The FEBS journal)

4.   Chakraborty P,  Dash, SP,  *Sarangi PP. The Role of Adhesion Protein Fibulin7 in Development and Diseases. Molecular Medicine 2020. 26 (47), 1-7 (Invited Review)

5.   Chakraborty P, Dalpati N, Bhan C, Dash SP, Kumar P, *Sarangi PP. A C-terminal fragment of adhesion protein Fibulin7 regulates neutrophil migration and functions and improves survival in LPS induced systemic inflammation. Cytokine. 2020.  131. 1551132

 

2019

6.   Chakraborty P, Dipankar P, Dash, SP, Priya, Srivastava S, Dhyani R, Navani N, Sharma D, *Sarangi PP. Electrostatic Surface Potential of Macrophages Correlates With Their Functional Phenotype. Inflammation. 2020 April;43 (2);641-650.

7.   Verma A, Ghosh T, Bhushan B, P. Gopinath P., Navani NK, Sarangi PP, Ambatipudi K. Characterization of Difference in Structure and Function of Fresh and Mastitic Bovine Milk Fat Globules. PLOS ONE. 2019 Aug 29;14(8)

8.   Bhan C, Dash SP, Dipankar P, Kumar P, Chakraborty P, *Sarangi PP. Investigation of extracellular matrix protein expression dynamics using murine models of systemic inflammation. Inflammation. 2019 Dec;42(6):2020-2031 

 

2018

9.   *Sarangi PP, Chakraborty P, Dash SP, Ambatipudi K, Vega SD, Ikeuchi T, Wahl L, *Yamada Y. Cell adhesion protein Fibulin-7 and its C-terminal fragment negatively regulate monocyte and macrophage migration and functions in vitro and in vivo. Sept 2018, 32(9). FASEB Journal. *Corresponding authors. (Highlighted in Nature-Asia/India)

 

2017

10.   Sarangi PP, Lee H, Lerman Y, Harrower E., Horrower E, Trzeciak A, Rezaie AR, Kim M. 2017. Activated protein C attenuates severe inflammation by selectively targeting VLA-3high neutrophil subpopulation in mice Journal of Immunology. Oct 15;199(8):2930-2936.

 

2016

11.   Bhan C, Dipankar P, Chakraborty P, *Sarangi PP. Role of Cellular events in the pathophysiology of sepsis. Inflammation Research. 2016, 65 (11), 853-868. 

 

2014

12.   Lerman YV, Lim, KH, Hyun YM, Falkner LK, Yang, H, Sonnenberg A, Pietropaoli A, *Sarangi PP, *Kim M. 2014. Sepsis lethality via exacerbated tissue infiltration and TLR-induced cytokine production by neutrophils is integrin α3β1-dependent. Blood. Dec;124; 3515-3523. *Co-Corresponding author (Highlighted in a commentary in The Blood journal)

 

Pre IIT Roorkee Publications

13.   *Sarangi PP, Hyun YM, Lerman Y LermanV, Pietropaoli A, *Kim M. 2012. Essential Role of integrin β1 in tissue homing of neutrophils during sepsis. Shock. Aug;38(3):281-7. *Co-Corresponding author

14.   Hyun, YM, Ronen Sumagin, Sarangi PP, Elena Lomakina E, Overstreet MG, Baker C, Fowell DJ, Waugh R, Sarelius IG, Kim M. 2012. Uropod Elongation is a common final step in leukocyte extravasation from inflamed vessels. Journal of Experimental Medicine. Jul 2;209(7):1349-62.

15.   Sarangi PP, Lee Hyun-wook and Kim M. 2010. Activated Protein C action in inflammation. British Journal of Hematology. 148(6):817-33.

16.   #Elphick GF, #Sarangi PP, Hyun Y, Hollenbaugh JA, Ayala A, Biffl WL, Chung H, Rezaie AR, McGrath JL, Topham DJ, Reichner JS, Kim M. 2009. Recombinant human activated protein C inhibits integrin-mediated neutrophil migration. Blood. 113(17):4078-85. #Co-First Author. (Cited in Nature’s Scibx Journal)

17.   Sarangi PP, Woo SR, Rouse BT. 2009. Modulation of herpes virus induced ocular immunopathology by anti-CD200R:Fc treatment. Clinical Immunology. 131(1):31-40.

18.   Sarangi PP, Kim B, Rouse BT. 2008. Modulation of herpes virus induced ocular immunopathology by non-mitogenic anti-CD3 monoclonal antibody treatment. Investigative Ophthalmology & Visual Science. 49(12):5425-33.

19.   Sarangi PP, Sehrawat S, Suvas S, Rouse BT. 2008. IL-10 and natural regulatory T cells: Two independent anti-inflammatory mechanisms in HSV induced ocular immunopathology. Journal of Immunology. 180(9):6297-306.

20.   Sehrawat S, Suvas S, Sarangi PP, Shuryawanshi A, Rouse BT. 2008. In vitro generated antigen specific CD4+CD25+Foxp3+ regulatory T cells control the severity of virus induced immunoinflammatory lesion. Journal of Virology. 82(14):6838-51.

21.   #Kim B, #Sarangi PP, Ahmet Kursat Azkur, Deshpande Kaistha S, Rouse BT. 2008. Enhanced viral immunoinflammatory lesions in mice lacking IL-23 responses. Microbes and infections. 10(3):302-312. #Co-First Author.

22.   Sarangi PP, Kim B., Kurt-Jones E, Rouse BT. 2007. Innate recognition network driving the HSV induced corneal immunopathology: Role of Toll Pathway in the early inflammatory events in Stromal Keratitis. Journal of Virology. 81(20):11128-38.

23.   Kim B, Sarangi PP, Y Lee Deshpande Kaistha S, Lee S, Rouse BT. 2006. Depletion of MCP-1 increases development of herpetic stromal keratitis by innate immune modulation. Journal of Leukocyte Biology. 80(6):1405-15. (Recommended in Faculty1000)

24.   Kim B, Suvas S, Sarangi PP, Lee S, Reisfield RA, Rouse BT. 2006. Vascular endothelial growth factor receptor2-based DNA immunization delays development of herpetic stromal keratitis by antiangiogenic effects. Journal of Immunology. 177(6):4122-31.

25.   Rouse BT, Sarangi PP, Suvas S. 2006. Regulatory T cells in virus infections. Immunological Reviews. 212:272-86.

26.   Suvas S, Kim B, Sarangi PP, Tone M, Waldmann, H, Rouse BT. 2005. In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology. Journal of Virology. 79(18):11935-42.

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